发明名称 |
ANTI-VAGINITIS COMPOSITIONS COMPRISING A TRIAZOLE |
摘要 |
The invention provides pharmaceutical compositions for topical administration in treating vaginal infections, e.g. vaginitis. Such compositions comprise: W at least one triazole compound active against Candida albicans, preferably at least one such compound which is additionally active against one or more non- albicans Candida species, and (ii) at least one additional anti-vaginitis medicament, preferably an anti-fungal, anti-protozoal and/or anti-bacterial agent. Preferred compositions include as active agents is terconazole in combination with tinidazole and/or tioconazole. In a further aspect the compositions in accordance with the invention also include a bioadhesive agent, e.g. a mucoadhesive, to promote adhesion to the vaginal mucosa. The use of a bioadhesive may also provide for controlled, e.g. rapid and/or delayed (sustained), release of the active agents. |
申请公布号 |
WO2005087270(A1) |
申请公布日期 |
2005.09.22 |
申请号 |
WO2004GB03972 |
申请日期 |
2004.09.17 |
申请人 |
EDKO TRADING AND REPRESENTATION CO. LTD.;EMBIL, KORAL;BAKTIR, GUL;FIGUEROA, RAY;GOLDING, LOUISE |
发明人 |
EMBIL, KORAL;BAKTIR, GUL;FIGUEROA, RAY |
分类号 |
A61K9/00;A61K31/4166;A61K31/4168;A61K31/4174;A61K31/4196;A61K45/06 |
主分类号 |
A61K9/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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