发明名称 N-terminal modification of RANTES and methods of use
摘要 N-terminally modified RANTES derivatives are disclosed. The derivatives effectively block the inflammatory effects of RANTES, and are useful for the treatment of asthma, allergic rhinitis, atopic dermatitis, atheroma/atherosclerosis, and rheumatoid arthritis. Additionally, the compounds are useful for the treatment of HIV infection.
申请公布号 US2005208016(A1) 申请公布日期 2005.09.22
申请号 US20050033877 申请日期 2005.01.13
申请人 GRYPHON THERAPEUTICS, INC. 发明人 OFFORD ROBIN E.;THOMPSON DARREN;WILKEN JILL
分类号 A61K38/00;A61K38/19;A61P9/10;A61P17/00;A61P29/00;A61P31/18;A61P37/08;C07K14/52;(IPC1-7):A61K38/19 主分类号 A61K38/00
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