发明名称 |
Factor IXa for the treatment of bleeding disorders |
摘要 |
The invention provides a method of treating bleeding disorders in a subject by administration of a preparation enriched for Factor IXa. The Factor IXa can be produced by proteolytically activating recombinantly-produced Factor IX. The invention also provides an improved method for producing Factor IXa from a plasma fraction, which method results in a Factor IXa product containing little or no prekallikrein activity, thus reducing the incidence of undesired side effects in a subject.
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申请公布号 |
US2005209149(A1) |
申请公布日期 |
2005.09.22 |
申请号 |
US20050068596 |
申请日期 |
2005.02.28 |
申请人 |
DONOVAN SHANE;BAKER DONALD A |
发明人 |
DONOVAN SHANE;BAKER DONALD A. |
分类号 |
A61K38/36;A61K38/48;(IPC1-7):A61K38/36 |
主分类号 |
A61K38/36 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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