CORNEAL EPITHELIAL SHEET, METHOD OF CONSTRUCTING THE SAME AND TRANSPLANTATION METHOD USING THE SHEET

摘要

It is intended to provide a corneal epithelial sheet having potential for the achievement of a favorable therapeutic effect and being highly safe in transplantation. Namely, a corneal epithelial sheet is constructed by: (a) preparing corneal epithelial cells; (b) separately culturing human fibroblasts in a collagen gel; (c) sowing or placing the corneal epithelial cells on the collagen gel; and (d) culturing and proliferating the corneal epithelial cells in the absence of heterologous animal cells.