发明名称 |
5-Protected aminopyrimidine compound, production method thereof and intermediate therefor |
摘要 |
The present invention provides a production method of 5-aminopyrimidine compound represented by the formula (5) by reacting a glycine compound represented by the formula (1) with t-butoxybisdimethylaminomethane, dimethylformamidedimethylacetal or dimethylformamidediethylacetal to produce a dialkylaminomethylene compound represented by the formula (2), reacting the compound of formula (2) in the presence of an acid to produce a hydroxymethylene compound represented by the formula (3), and reacting the compound of formula (3) with an amidine compound represented by the formula (4) or a salt thereof.
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申请公布号 |
US2005209257(A1) |
申请公布日期 |
2005.09.22 |
申请号 |
US20050081616 |
申请日期 |
2005.03.17 |
申请人 |
AJINOMOTO CO., INC. |
发明人 |
TAKAHASHI DAISUKE;IZAWA KUNISUKE |
分类号 |
C07D239/46;C07D239/47;(IPC1-7):A61K31/513 |
主分类号 |
C07D239/46 |
代理机构 |
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代理人 |
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地址 |
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