发明名称 |
CLASSIFICATION OF BREAST CANCER PATIENTS USING A COMBINATIONOF CLINICAL CRITERIA AND INFORMATIVE GENESETS |
摘要 |
The present invention provides prognostic methods for conditions such as cancer, for example, breast cancer, comprising classifying an individual by a plurality of phenotypic, genotypic or clinical characteristics of the condition into a plurality of patient subsets, and analyzing the pattern of expression of prognosis-informative genes identified for that subset in a sample from the individual. The present invention also provides methods for constructing such patient subsets and of identifying prognosis-informative genesets for such subsets. The invention further provides methods of assigning a therapeutic regimen to an individual, microarrays useful for performing prognosis, kits comprising these microarrays, and computer systems and programs for implementing the methods of the invention. |
申请公布号 |
CA2558808(A1) |
申请公布日期 |
2005.09.22 |
申请号 |
CA20052558808 |
申请日期 |
2005.03.07 |
申请人 |
ROSETTA INPHARMATICS, LLC;THE NETHERLANDS CANCER INSTITUTE |
发明人 |
VAN'T VEER, LAURA J.;HE, YUDONG;DAI, HONGYUE;FRIEND, STEPHEN H.;STOUGHTON, ROLAND;LAMB, JOHN |
分类号 |
C12Q1/68;G01N33/574 |
主分类号 |
C12Q1/68 |
代理机构 |
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