| 发明名称 |
7-Substituted camptothecin and camptothecin analogs and methods for producing the same |
| 摘要 |
Methods of forming camptothecin compounds which are effective anti-tumor compounds are disclosed. These compounds inhibit the enzyme topoisomerase I and may alkylate DNA of the associated topoisomerase I-DNA cleavable complex.
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| 申请公布号 |
US2005209263(A1) |
申请公布日期 |
2005.09.22 |
| 申请号 |
US20050130126 |
申请日期 |
2005.05.17 |
| 申请人 |
RESEARCH TRIANGLE INSITUTE |
发明人 |
WANI MANSUKH C.;MANIKUMAR GOVINDARAJAN;WALL MONROE E.;WALL MICHAEL A. |
| 分类号 |
C07D491/22;(IPC1-7):A61K31/474;C07D491/14 |
主分类号 |
C07D491/22 |
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