发明名称 |
STABILISED SUPERSATURATED SOLIDS OF LIPOPHILIC DRUGS |
摘要 |
The present invention relates to a pharmaceutical composition with improved dissolution of lipophilic drugs in an aqueous medium. It is found that pharmaceutical compositions comprising a powder of lipophilic compounds, such as hormones and steroids (e.g. drospirenone and estradiol valerate), on molecularly dispersed form together with a carrier having a specific surface area of at least 250 m<2>/g, such as silica dioxide, e.g. silica dioxide marketed under the name Aeroperl(R), has improved dissolution properties of the lipophilic drug. |
申请公布号 |
WO2005087199(A2) |
申请公布日期 |
2005.09.22 |
申请号 |
WO2005IB00748 |
申请日期 |
2005.03.10 |
申请人 |
SHERING AKTIENGESELLSCHAFT;FUNKE, ADRIAN;WAGNER, TORSTEN;LIPP, RALPH |
发明人 |
FUNKE, ADRIAN;WAGNER, TORSTEN;LIPP, RALPH |
分类号 |
A61K9/08;A61K9/14;A61K31/565;A61K31/585;A61K47/10;A61K47/14;A61K47/44 |
主分类号 |
A61K9/08 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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