Human cancer-related genes, the products encoded thereby and applications thereof

摘要

The invention discloses a human cancer-related gene, LAPTM4B , its encoded products and their applications thereof. This human cancer-related gene provided by this invention comprises one of the following nucleotide sequences: (1) SEQ ID N o : 1, SEQ ID N o : 2, SEQ ID N o : 3, SEQ ID N o : 6, or SEQ ID N o : 8 in the sequence listings; (2) Polynucleotides that encode the protein sequences of SEQ ID N o : 4, SEQ ID N o : 5, or SEQ ID N o : 7 in the sequence listings; (3) DNA sequences having above 90% homology with the DNA sequences specified by SEQ ID N o : 1, SEQ ID N o : 2, SEQ ID N o : 3, SEQ ID N o : 6, or SEQ ID N o : 8 in the sequence listings, and these DNA sequences encode the proteins with the same or similar functions. This invention enables the developments of new anti-cancer approaches and new anti-cancer medicines. It would create a significant impact on human society.