发明名称 Use of D4 and 5-HT2A antagonists, inverse agonists or partial agonists
摘要 <p>The present invention relates to the use of compounds and compositions of compounds having D4 and/or 5-HT2A antagonistic, partial agonistic or inverse agonistic activity in combination with other compounds for treating neurodegenerative diseases or disorders, such as Parkinson disease and related cognitive diseases or disorders. The invention also relates to pharmaceutical compositions for administration to a patient diagnosed as having a neurodegenerative disease or disorder and/or a cognitive disease or disorder, said pharmaceutical composition containing (&lt;Bold&gt;i&lt;/Bold&gt;) compounds having D4 antagonistic, partial agonistic or inverse agonistic activity and/or (ii) compounds having 5-HT2A antagonistic, partial agonistic or inverse agonistic, and/or (iii) any known medicinal compound or compositions of said compounds in combination with another compound for treating said diseases or disorders to augment the therapeutic effect or to provide a faster onset of the therapeutic effect of said other compound.</p>
申请公布号 EP1576985(A1) 申请公布日期 2005.09.21
申请号 EP20040447066 申请日期 2004.03.18
申请人 B&B BEHEER NV 发明人 BUNTINX, ERIK
分类号 A61K31/00;A61K31/4545;A61P25/28;(IPC1-7):A61P25/28;A61K31/454 主分类号 A61K31/00
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