| 摘要 |
FIELD: chemistry of peptides, medicine. ^ SUBSTANCE: invention relates to compound of the structure: N-methyl-(D-Leu-D-Val-D-Phe-D-Phe-D-leu)-NH2 designated for using as an active component in manufacturing a medicinal agent used for inhibition of natural beta-amyloid peptides aggregation in patients suffering with disorder associated with beta-amyloidosis and in treatment of Alzheimer's disease. Also, invention relates to a pharmaceutical composition, a method for inhibition of natural beta-amyloid peptides, a method for detection of natural beta-amyloid, a method for detection for the presence or absence of natural beta-amyloid peptides in biological sample and to a method for treatment of patient with disorder associated with beta-amyloidosis. ^ EFFECT: improved method for detecting, valuable medicinal properties of agent. ^ 14 cl, 5 tbl, 5 dwg, 9 ex |
