发明名称 |
BENZAMIDE DERIVATIVE-CONTAINING PHARMACEUTICAL COMPOSITION ELICITING ENHANCED SOLUBILITY AND ABSORPTION CAPACITY IN ORAL APPLYING |
摘要 |
FIELD: chemical-pharmaceutical industry, pharmacy. ^ SUBSTANCE: invention relates to a new pharmaceutical composition comprising benzamide derivative and one or some additives taken among the following substances: 1) mixture of polyethylene glycol and surface-active substance; 2) amino acid or inorganic acid salt, and 3) propylene carbonate. The composition comprises benzamide derivative taken in the amount from 0.001 to 1000 mg per a single dosing formulation. The composition shows the enhanced solubility and absorption capacity in oral route of administration. ^ EFFECT: improved medicinal and pharmaceutical properties of composition. ^ 9 cl, 4 tbl, 1 dwg, 5 ex |
申请公布号 |
RU2260428(C2) |
申请公布日期 |
2005.09.20 |
申请号 |
RU20020107992 |
申请日期 |
2000.08.29 |
申请人 |
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发明人 |
ISIBASI MASAKHIKO;SAKABE MASAKHIRO;SAKAI IKUO;SUZUKI TSUNEDZI;ANDO TOMOJUKI |
分类号 |
A61K47/00;A61K9/08;A61K9/20;A61K9/48;A61K9/66;A61K31/4406;A61K31/4418;A61K47/04;A61K47/10;A61K47/12;A61K47/16;A61K47/18;A61K47/20;A61K47/22;A61K47/26;A61K47/34;A61K47/36;A61K48/00;A61P35/00;A61P37/06;A61P43/00;C07D213/30;C07D213/65;C07D213/75 |
主分类号 |
A61K47/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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