发明名称 Thio-oxindole derivatives
摘要 This invention relates to methods of co-administering compounds of formula 1 which are agonists of the progesterone receptor which have the general structure: wherein: R<SUB>1</SUB>, R<SUB>2</SUB>, R<SUB>3</SUB>, R<SUB>4</SUB>, R<SUB>5 </SUB>and Q<SUP>1 </SUP>are as defined herein, or a pharmaceutically acceptable salt thereof, with estrogen, an estrogen, or an estrogen receptor agonist for contraception, hormone replacement therapy, or treating progesterone-related carcinomas and adenocarcinomas.
申请公布号 US6946454(B2) 申请公布日期 2005.09.20
申请号 US20020117156 申请日期 2002.04.05
申请人 LIGAND PHARMACEUTICALS, INC. 发明人 FENSOME ANDREW;ZHANG PUWEN;KOKO MARCI C.;ZHI LIN;JONES TODD K.;WROBEL JAY E.;TEGLEY CHRISTOPHER M.;EDWARDS JAMES P.;MELENSKI EDWARD G.
分类号 C07D409/10;A61K31/404;A61P1/00;A61P5/34;A61P5/36;A61P7/00;A61P7/04;A61P13/08;A61P15/00;A61P35/00;A61P43/00;C07D209/08;C07D209/30;C07D209/40;C07D209/96;(IPC1-7):A61K31/56;A61K31/44;A61K31/40 主分类号 C07D409/10
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