| 发明名称 |
ФАРМАЦЕВТИЧЕСКАЯ КОМПОЗИЦИЯ, ВКЛЮЧАЮЩАЯ КРИСТАЛЛИЧЕСКИЙ ПОЛУГИДРАТ МЕТАНСУЛЬФОНАТА СИБУТРАМИНА |
| 摘要 |
The present invention relates to a pharmaceutical composition for treating or preventing obesity, comprising novel crystalline sibutramine methanesulfonate hemihydrate of formula (I). The crystalline sibutramine methanesulfonate hemihydrate according to the present invention has a much higher solubility in water, and enhanced stability under a high humidity/temperature condition, as compared with sibutramine hydrochloride monohydrate |
| 申请公布号 |
RU2005109560(A) |
申请公布日期 |
2005.09.20 |
| 申请号 |
RU20050109560 |
申请日期 |
2003.09.25 |
| 申请人 |
ХАНМИ ФАРМ. КО., ЛТД. (KR) |
发明人 |
ЛИ Дзае-Хеон (KR);ПАРК Га-Сеунг (KR);ЛИ Дзае-Чеол (KR);КИМ Хан-Киунг (KR);ЧАНГ Янг-Кил (KR);ЛИ Гван-Сун (KR) |
| 分类号 |
A61K31/13;A61K31/205 |
主分类号 |
A61K31/13 |
| 代理机构 |
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