发明名称 Substituted biphenyl derivatives
摘要 The invention relates to compounds of the formula I in which R<SUP>1</SUP>, R<SUP>2</SUP>, R<SUP>3</SUP>, R<SUP>4 </SUP>and X have the meaning indicated in the text. The compounds act as inhibitors of factors Xa and VIIa and can therefore be employed for the control and prevention of thromboembolic conditions such as thrombosis, myocardial infarct, arteriosclerosis, inflammation, apoplexy, angina pectoris, restenosis after angioplasty and intermittent claudication.
申请公布号 US6946489(B2) 申请公布日期 2005.09.20
申请号 US20030239397 申请日期 2003.01.14
申请人 MERCK PATENT GMBH 发明人 JURASZYK HORST;DORSCH DIETER;MEDERSKI WERNER;TSAKLAKIDIS CHRISTOS;BAMES CHRISTOPHER;GLEITZ JOHANNES
分类号 C07D317/60;A61K31/167;A61K31/216;A61K31/235;A61K31/27;A61K31/36;A61P7/02;A61P9/08;A61P9/10;A61P29/00;A61P43/00;C07C257/18;C07C317/32;C07C317/40;(IPC1-7):A61K31/165;C07C233/00 主分类号 C07D317/60
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