PHARMACEUTICAL OCULAR PREPARATIONS SUITABLE FOR THE TREATMENT OF THE OCULAR SURFACE AND RELATED DISORDERS/DISEASES

摘要

A pharmaceutical preparation suitable for use in the eye, which comprises: ( i) a pharmaceutically acceptable carrier suitable for use in the eye; (ii) one or more ingredients selected from factors and agents that promote any one or mo re of survival, health, cell attachment and normal differentiation of ocular surface epithelial cells and optionally factors and agents to prevent squamo us metaplasia; (iii) one or more agents capable of altering the fluid propertie s of a tear film including at least one agent capable of establishing and/or maintaining a stable tear film and optionally one or more agents selected fr om ophthalmological lubricating agents, viscosity enhancing agents and agents capable of reducing tear film evaporation; the factors and agents in compone nt (ii) and (iii) being synthetic or recombinant or licensed for pharmaceutical use.