Matrix structure and hybrid matrix system for inducing a neofacia, their use and method for generating a neofacia

摘要

The invention is directed to a matrix structure for inducing a neofascia with at least one two-dimensional matrix of at least one biocompatible and resorbable polymer, wherein the surface of the matrix is designed to immobilize tissue cells, in particular autologous fibrocytes of the fascia transversalis, and to reduce a preferably three-dimensional tissue growth in vitro or in vivo. The invention is also directed to a hybrid matrix system, which includes the matrix structure and tissue cells immobilized thereon. The novel matrix as well as the fascia hybrid are characterized by a high biocompatibility and overcome the disadvantages of non-degradable implants, thereby promoting formation of a neofascia with native biomechanical properties.