发明名称 |
Contrast agents |
摘要 |
Microbubble dispersions stabilised by phospholipids predominantly comprising molecules which individually have an overall net charge exhibit advantageous stability, rendering them useful as efficacious contrast agents. An improved process for preparing microbubble-containing contrast agents is also disclosed, this comprising lyophilising an aqueous dispersion of gas microbubbles stabilised by one or more membrane-forming lipids to yield a dried product which may be reconstituted in an injectable carrier liquid to generate a microbubble-containing contrast agent.
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申请公布号 |
US2005201942(A1) |
申请公布日期 |
2005.09.15 |
申请号 |
US20050073027 |
申请日期 |
2005.03.04 |
申请人 |
DUGSTAD HARALD;KLAVENESS JO;RONGVED PAL;SKURTVEIT ROALD;BRAENDEN JORUNN |
发明人 |
DUGSTAD HARALD;KLAVENESS JO;RONGVED PAL;SKURTVEIT ROALD;BRAENDEN JORUNN |
分类号 |
A61K47/24;A61K49/00;A61K49/04;A61K49/22;(IPC1-7):A61K49/04 |
主分类号 |
A61K47/24 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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