| 发明名称 |
USE OF 1-ADAMANTYLETHOXY-3-DIALKYLAMINO-2-PROPANOLS AS ACTOPROTECTORS |
| 摘要 |
The invention relates to the organic chemistry, in particular to derivatives of 1-adamantyethoxy-3-dialkylamino-2-propanol, which have as dialkylamino substituent morpholine (I), diethylamine (II), [N-3-chlorophenyl]piperazine (III) and [N-2-fluorophenyl] piperazine (IV), revealing actoprotector action and can be used as actoprotectors . Proposed compounds (I-IV) exceed bemityl test ûpreparation as per value of ED50 respectively by 12.0; 5.9; 1.67; 13.4 times.
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| 申请公布号 |
UA75943(C2) |
申请公布日期 |
2005.09.15 |
| 申请号 |
UA20040021174 |
申请日期 |
2004.02.18 |
| 申请人 |
M.I. PYROGOV VINNYTSIA STATE MEDICAL UNIVERSITY;INSTITUTE OF ORGANIC CHEMISTRY OF THE NATIONAL ACADEMY OF SCIENCES OF UKRAINE |
发明人 |
STEPANIUK HEORHII IVANOVYCH;KOROTKYI YURII VASYLIOVYCH;DRACHUK OLHA PETRIVNA;STEPANIUK NATALIIA HEORHIIVNA;SERHIEEV SERHII VALERIIOVYCH;LOZYNSKYI MYRON ONUFRIIOVYCH |
| 分类号 |
A61K31/075;A61K31/535;A61P37/02;C07C13/00;C07D295/084 |
主分类号 |
A61K31/075 |
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