AMINE-BASED BASIC COMPOUND AND USE THEREOF

摘要

A novel amine compound represented by the following general formula (1), whi ch is effective in HIV viral infectious diseases and diseases such as rheumatis m or cancer metastasis. [Chemical formula 1] (1) Typically, A1 and A2 each represents hydrogen or an optionally substituted, monocyclic or polycyclic, heteroaromatic ring and W represents an optionally substituted benzene ring or a group represented by the following (10) or (11). [Chemical formula 2] (10) [Chemical formula 3] (11) X represents oxygen, CH2, C(=O), NR11, or CHR35 an d D represents a group represented by the following formula (6). [Chemical formula 4] (6) In the formula (6), Q represents a single bond, NR12, or the formula (13): [Chemical formula 5] (13) Y represents a group represented by the following formula (7): [Chemical formula 6] or (7) (wherein Z represents an optionally substituted, monocyclic or polycyclic aromatic ring), and B represents -NR25R26. In these formulae, R1 to R26 each represents hydrogen, alkyl, alkenyl, or alkynyl.