发明名称 |
Viral vectors having reduced virulence |
摘要 |
The present invention provides recombinant vaccinia virus having a deletion of the region encoding the C-terminal seven amino acids of the E3L gene product and comprising exogenous DNA. Compositions comprising the recombinant vaccinia virus and methods of use thereof are also provided.
|
申请公布号 |
US6942855(B2) |
申请公布日期 |
2005.09.13 |
申请号 |
US20040830547 |
申请日期 |
2004.04.23 |
申请人 |
|
发明人 |
|
分类号 |
C12N15/09;A61K35/76;A61K38/00;A61K48/00;C12N7/01;C12N7/04;C12N15/863;C12P21/02;(IPC1-7):A61K48/00 |
主分类号 |
C12N15/09 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|