PROCESS FOR THE PREPARATION OF PYRUVIC ACID

摘要

A process for the production of pyruvic acid involving the enzymatic reactio n of L-lactic acid and oxygen in an aqueous solution in the presence of catalysts glycolate oxidase ((S)2-hydroxy-acid oxidase, EC 1.1.3.15) and catalase (EC 1.11.1.6). High yields of pyruvate (e.g., 96 %) at high purity (98 % sodium salt) can be achieved at commercial ly acceptable concentration (typically up to0.5M) without substantial product inhibition of the enzyme.