发明名称 ИСПОЛЬЗОВАНИЕ УРЕАЗЫ ДЛЯ УГНЕТЕНИЯ РОСТА РАКОВЫХ КЛЕТОК
摘要 A pharmaceutical composition and method for use in inhibiting growth of cancer cells in a mammalian subject are disclosed. The composition includes a urease enzyme, and associated therewith, a chemical entity effective to enhance the delivery of the enzyme to cancer cells, when the composition is administered to the subject. Also disclosed are a method of enhancing the effectiveness of weakly basic anti-tumor compounds, a method assessing the presence, size or condition a solid tumor in a subject, and a gene therapy composition for treating a cancer in a subject.
申请公布号 RU2005104113(A) 申请公布日期 2005.09.10
申请号 RU20050104113 申请日期 2003.07.16
申请人 ХЕЛИКС БИОФАРМА КОРП. (CA) 发明人 ЧАО Герман (CA);ВОНГ Вах (CA);СЕГАЛ Дональд (CA);МАКЭЛРОЙ Джерри (CA);ДОЧЕРТИ Джон (CA);ДИКСТЕЙН Джоди (CA)
分类号 A61K38/50;A61K47/48;A61K48/00;A61P35/00 主分类号 A61K38/50
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