发明名称 |
STRONTIUM-CONTAINING COMPOUNDS FOR USE IN THE PREVENTION OR TREATMENT OF NECROTIC BONE CONDITIONS |
摘要 |
<p>A method for the treatment and/or prophylaxis of an ostenonecrotic bone disease in a mammal in need thereof, such as, e.g., idiopathic or secondary osteonecrosis, avascular bone necrosis, glucocorticoid induced bone ischemia/osteonecrosis, Legg-Calve-Perthes disease and femoral head necrosis, the method comprising administering an effective dose of a strontium-containing compound (a) to the mammal. A method for the treatment and/or prophylaxis of an osteonecrotic bone disease, such as, e.g., idiopathic or secondary osteonecrosis, avascular bone necrosis, glucocorticoid induced bone ischemia/osteonecrosis and femoral head necrosis, in a mammal who is to be or is treated with a therapeutic agent (b) known to or suspected of inducing apoptosis and/or necrosis of bone cells, the method comprising administering a strontium-containing compound (a) in combination with (b).</p> |
申请公布号 |
WO2005082385(A1) |
申请公布日期 |
2005.09.09 |
申请号 |
WO2005DK00140 |
申请日期 |
2005.02.28 |
申请人 |
OSTEOLOGIX A/S;HANSEN, CHRISTIAN;NILSSON, HENRIK;CHRISTGAU, STEPHAN;BONE, HENRY, G., III |
发明人 |
HANSEN, CHRISTIAN;NILSSON, HENRIK;CHRISTGAU, STEPHAN;BONE, HENRY, G., III |
分类号 |
A61K31/28;A61K31/56;A61K31/57;A61K31/663;A61K33/24;A61K45/06;(IPC1-7):A61K33/24 |
主分类号 |
A61K31/28 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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