| 发明名称 |
Gyrase inhibitors and uses thereof |
| 摘要 |
The present invention relates to compounds of the formula I:where Ring A is a thiazole, oxazole, imidazole or pyrazole and the substituents are as described in the specification, and pharmaceutically acceptable salts thereof. The compounds inhibit bacterial gyrase activity and therefore are useful for treating bacterial infections in mammals. |
| 申请公布号 |
AU782883(B2) |
申请公布日期 |
2005.09.08 |
| 申请号 |
AU20010030940 |
申请日期 |
2001.01.16 |
| 申请人 |
VERTEX PHARMACEUTICALS INCORPOATED |
发明人 |
PAUL CHARIFSON;DEAN STAMOS;MICHAEL BADIA;ANNE-LAURE GRILLOT;STEVEN RONKIN;MARTIN TRUDEAU |
| 分类号 |
C07D231/38;A61K31/4155;A61K31/421;A61K31/422;A61K31/427;A61K31/454;A61K31/5377;A61P1/00;A61P11/00;A61P13/02;A61P13/08;A61P17/00;A61P17/02;A61P19/02;A61P19/08;A61P25/00;A61P31/04;A61P31/06;A61P43/00;C07D403/04;C07D413/04;C07D417/04;C07D417/14;(IPC1-7):A61K31/415 |
主分类号 |
C07D231/38 |
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