| 摘要 |
<p>A pharmaceutical composition with antitumor activity based on carboplatin and comprising an aqueous solution of carboplatin with the carboplatin content from 1 to 20 mg ml-1 whereby it contains immediately after its preparation less than 0,1 % by weight of impurities causing a nucleophilic substitution of the carboxylate ligand of carboplatin, especially 1,1-cyclobutandicarboxylic acid and/or a salt thereof, the impurities being exclusively formed by accompanying impurities incorporated into carboplatin, as comprised in the pharmaceutical composition, during the production of carboplatin.</p> |
