| 发明名称 |
CHIMERIC AND HUMANIZED ANTIBODIES TO alpha5beta1 INTEGRIN THAT MODULATE ANGIOGENESIS |
| 摘要 |
<p>The present invention provides chimeric and humanized antibodies that specifically recognize alpha5beta1 integrin, and methods for using the antibodies for reducing or inhibiting angiogenesis in a tissue. Also provided are methods of determining therapeutically acceptable doses of the antibodies and pharmaceutical compositions including the same.</p> |
| 申请公布号 |
KR20050089151(A) |
申请公布日期 |
2005.09.07 |
| 申请号 |
KR20057009577 |
申请日期 |
2005.05.26 |
| 申请人 |
PROTEIN DESIGN LABS, INC. |
发明人 |
RAMAKRISHNAN VANITHA;POWERS DAVID;JOHNSON DALE E.;JEFFRY URSULA |
| 分类号 |
C07K16/28;C07K16/42;(IPC1-7):A61K39/395 |
主分类号 |
C07K16/28 |
| 代理机构 |
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