发明名称 |
FLUORESCENT INDICATOR USING FRET |
摘要 |
<p>It is an object of the present invention to provide a fluorescent indicator that is based on homo FRET (fluorescence resonance energy transfer) using fluorescent molecules with a small stokes' shift, thereby developing a visualization system for intermolecular interaction. The present invention provides a fluorescent indicator formed by fusing fluorescent molecular components having substantially identical fluorescent properties to the N- and C-terminal sides of a target sequence, to which an analytical substance binds or reacts, so as to change the three-dimensional structure of the indicator. <IMAGE></p> |
申请公布号 |
EP1571448(A1) |
申请公布日期 |
2005.09.07 |
申请号 |
EP20030778776 |
申请日期 |
2003.12.10 |
申请人 |
RIKEN;JAPAN SCIENCE AND TECHNOLOGY AGENCY |
发明人 |
MIYAWAKI, ATSUSHI;NAGAI, TAKEHARU |
分类号 |
G01N21/64;C07K14/435;C12N1/15;C12N1/19;C12N1/21;C12N5/10;C12N15/09;G01N21/78;G01N33/483;G01N33/542;G01N33/68;(IPC1-7):G01N33/68 |
主分类号 |
G01N21/64 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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