发明名称 |
USE OF IL-2 RECEPTOR ANTIBODIES TO PREVENT TOXICITY ASSOCIATED WITH AMPHOTERICIN B ANTIMYCOTIC THERAPY |
摘要 |
This invention relates to a method for treating a patient having a fungal infection. The invention comprises administering to the patient a therapeutically effective amount of a polyene antifungal (e.g., amphotericin B) in association with a therapeutically effective amount of a interleukin-2 inhibitor (e.g., chimeric or humanized monoclonal antibody that binds to the p55 subunit of the human interleukin-2 receptor and inhibits binding of interleukin-2 to an interleukin-2 receptor).
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申请公布号 |
KR20050089148(A) |
申请公布日期 |
2005.09.07 |
申请号 |
KR20057005682 |
申请日期 |
2005.04.01 |
申请人 |
F. HOFFMANN-LA ROCHE AG;THE UNIVERSITY OF MISSISSIPPI MEDICAL CENTER;THE UNIVERSITY OF MISSISSIPPI |
发明人 |
CHAPMAN STANLEY WILLETTS;CLEARY JOHN D.;GORDON ROBERT D. |
分类号 |
A61K31/7048;A61K39/395;A61P33/00;(IPC1-7):A61K31/704 |
主分类号 |
A61K31/7048 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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