发明名称 Polymorphic forms of sertraline hydrochloride
摘要 A crystalline form of sertraline hydrochloride was found, referred to hereinafter as polymorphic form CSC2 having a dissolution rate which surprisingly will increase rate of absorption of a drug. Furthermore, different crystalline forms of sertraline hydrochloride alcohol solvates, crystalline forms of sertraline hydrochloride hydrates, referred to hereinafter as polymorphic form CSC1, a process for the preparation of the amorphous form of sertraline hydrochloride, and different processes for the preparation of polymorphic forms I, II, V, and T1 are disclosed.
申请公布号 US6939992(B2) 申请公布日期 2005.09.06
申请号 US20030736195 申请日期 2003.12.15
申请人 CIBA SPECIALTY CHEMICALS CORPORATION 发明人 VAN DER SCHAAF PAUL ADRIAAN;SCHWARZENBACH FRANZ;KIRNER HANS-JOERG;SZELAGIEWICZ MARTIN;MARCOLLI CLAUDIA;BURKHARD ANDREAS
分类号 A61P3/04;A61K31/135;A61K31/137;A61P15/10;A61P25/22;A61P25/24;A61P25/30;C07C209/84;C07C211/42;(IPC1-7):C07C211/00 主分类号 A61P3/04
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