发明名称 |
CONTROLLED-RELEASE COMPOSITIONS |
摘要 |
A solid dosage formulation having a core with a pharmacological agent dispersed in a first controlled-release matrix from which release of the agent is relatively slow; and a coat formed over the core and having the agent dispersed in a second controlled-release matrix from which release of the agent is relatively fast. The first matrix can be a cross-linked high amylose starch and the second matrix can be a mixture of polyvinyl acetate and polyvinylpyrrolidone.
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申请公布号 |
KR20050088281(A) |
申请公布日期 |
2005.09.05 |
申请号 |
KR20057007088 |
申请日期 |
2003.10.27 |
申请人 |
LABOPHARM INC.;LABOPHARM (BARBADOS) LIMITED;LABOPHARM EUROPE LIMITED |
发明人 |
LENAERTS VINCENT;OUADJI NJIKI PATRICIA LAURE;BACON JONATHAN;OUZEROUROU RACHID;GERVAIS SONIA;RAHMOUNI MILOUD;SMITH DAMON |
分类号 |
A61K;A61K9/20;A61K9/22;A61K9/24;A61K9/28;(IPC1-7):A61K9/00 |
主分类号 |
A61K |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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