<p>Disclosed is a compound represented by the general formula (I) below which is useful as a neurokinin receptor antagonist. [In the above formula, R<1> and R<2> respectively represent an optionally substituted (hetero)aryl group; R<3> represents -CO-R<4>, -CO-O-R<4> or the like; R<4> represents an alkyl group, cycloalkyl group or the like; A represents CH2, CO or SO2; B represents a single bond or the like; D represents an oxygen atom or CH2; E represents an alkylene group or alkenylene group; and n represents an integer of 1-3.]</p>