发明名称 AMIDINE DERIVATIVES FOR TREATING AMYLOIDOSIS
摘要 <p>The present invention relates to the use of amidine compounds in the treatment of amyloid-related diseases. In particular, the invention relates to a method of treating or preventing an amyloid-related disease in a subject comprising administering to the subject a therapeutic amount of an amidine compound. Among the compounds for use according to the invention are those according to the following Formula (I), such that, when administered, amyloid fibril formation, neurodegeneration, or cellular toxicity is reduced or inhibited: Formula (I).</p>
申请公布号 WO2005079780(A1) 申请公布日期 2005.09.01
申请号 WO2004IB00617 申请日期 2004.01.23
申请人 NEUROCHEM (INTERNATIONAL) LIMITED;KONG, XIANQI;WU, XINFU;MIGNEAULT, DAVID 发明人 KONG, XIANQI;WU, XINFU;MIGNEAULT, DAVID
分类号 A61K31/155;A61K31/167;A61K31/18;A61K31/4168;A61P3/10;A61P5/50;A61P25/28;A61P43/00;(IPC1-7):A61K31/155;A61K31/416 主分类号 A61K31/155
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