发明名称 |
SENSORS FOR BIOMOLECULAR DETECTION AND CELL CLASSIFICATION |
摘要 |
A sensor device is provided for detecting an analyte in a sample in which an analyte is bound to a detection reagent to form a bound complex. The device comprises (a) a sample (5) comprising an ionic analyte and a detection reagent in a conductive fluid, wherein the detection reagent has a net charge différent from the analyte; (b) a first permeable polymeric hydrogel plate (3) and a first spacer plate (8), which plates provide a compartment for the sample; (c) an anode (1) juxtaposed to the outside of the first hydrogel plate and not in contact with the sample; (d) a cathode (9) juxtaposed to the outside of the first spacer plate and not in contact with the sample; (e) a voltage generator (10) to apply an electric potential to the anode and cathode; and (f) a detector (11). The bound complex formed from the analyte and detection reagent is detected by the detector because the bound complex has a charge that causes it to migrate in a direction opposite from that of the unbound analyte when the electric potential is applied. |
申请公布号 |
WO2005080546(A1) |
申请公布日期 |
2005.09.01 |
申请号 |
WO2003US31486 |
申请日期 |
2003.10.03 |
申请人 |
MOYLE, WILLIAM, R. |
发明人 |
MOYLE, WILLIAM, R.;SCADUTO, RUSSEL, C., JR. |
分类号 |
B01D59/42;C02F1/40;C12M1/34;G01N27/447 |
主分类号 |
B01D59/42 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|