发明名称 |
A METHOD FOR OXYGEN REGULATED PRODUCTION OF RECOMBINANT STAPHYLOKINASE |
摘要 |
The present invention relates to a nucleotide sequence of expression cassette OXY-1 of SEQ ID No. 1, a modified staphylokinase SAK-2 gene of SEQ ID No. 2, a peptide sequence of modified staphylokinase SAK-2 gene, of SEQ ID No. 3, three plasmids having International Deposition Nos. BPL-0019, BPL-0020, and BPL-0021, and their corresponding three recombinant E. Coli; also invention relates to a process for over-producing staphylokinase and its analogues by modulating level of oxygen of its growth medium in a host system, and lastly, a method of dissolving blood clot in a subject in need thereof. |
申请公布号 |
WO2004087750(A3) |
申请公布日期 |
2005.09.01 |
申请号 |
WO2004IN00077 |
申请日期 |
2004.03.31 |
申请人 |
COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH;RAJAMOHAN, GOVINDAN;DAHIYA, MONIKA;PATHANIA, RANJANA;DIKSHIT, KANAK, LATA |
发明人 |
RAJAMOHAN, GOVINDAN;DAHIYA, MONIKA;PATHANIA, RANJANA;DIKSHIT, KANAK, LATA |
分类号 |
C07K14/31;C12N9/70 |
主分类号 |
C07K14/31 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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