CROSSLINKED POLYROTAXANE AND PROCESS FOR PRODUCING THE SAME

摘要

A compound or material having safety, namely, biocompatibility that exhibits such a nongel-gel transition that the state of being nongel is presented on the side of low temperature while the state of being crosslinked, for example, gel is presented on the side of high temperature. There is provided a crosslinked polyrotaxane comprising at least two molecules of polyrotaxane consisting of cyclodextrin molecules having a linear molecule enclosed in the form of a skewer in cavities thereof and having block groups arranged at both ends of the linear molecule so as to prevent detachment of the cyclodextrin molecules, the above at least two molecules of polyrotaxane crosslinked with each other via physical bonds, characterized in that the hydroxyls (-OH) of the cyclodextrin molecules are partially or wholly substituted with nonionic groups.