The functional characteristics of heme proteins can be modified to produce hemoglobins that can be used as blood substitutes in different therapeutic applications. Stable polymers of tetrameric hemoglobin, and of myoglobin molecules, are provided for use in the blood substitutes.
申请公布号
WO2005041898(A3)
申请公布日期
2005.09.01
申请号
WO2004US36544
申请日期
2004.11.01
申请人
TEMPLE UNIVERSITY OF THE COMMONWEALTH SYSTEM;JOHNS OPKINS UNIVERSITY LTD;FRONTICELLI, CLARA;BRINIGAR, WILLIAM, S.