| 发明名称 |
ANTIBODIES SPECIFIC FOR CD44V6 |
| 摘要 |
The present invention belongs to the field of oncology. The invention relates to antibodies with specified sequence which are specific for an epitope which is coded by the variant exon v6 of the CD44gene and to derivatives of said antibody. The invention also provides nucleic acid molecules encoding said antibody proteins. The invention furthermore pertains to methods for producing said antibody proteins. The invention also provides pharmaceutical compositions comprising said antibody proteins. The invention furthermore is concerned with the use in the manufacture of a medicament for the treatment of cancer. |
| 申请公布号 |
HRP20030931(A2) |
申请公布日期 |
2005.08.31 |
| 申请号 |
HR2003P000931 |
申请日期 |
2003.11.14 |
| 申请人 |
BOEHRINGER INGELHEIM PHARMACEUTICALS INC. BOEHRINGER INGELHEIM INTERNACIONAL GMBH |
发明人 |
GUENTHER ADOLF;ELINBORG OSTERMANN;ERIK PATZELT;MARLIES SPROLL;KARL-HEINZ HEIDER;MIGLIETTA J JOHN;AUGUSTINUS ANTONIUS MARIA SILV VAN DONGEN |
| 分类号 |
C12N15/09;A61K31/375;A61K39/395;A61K47/48;A61K51/00;A61P35/00;A61P35/04;C07K16/18;C07K16/28;C07K16/46;C07K19/00;C12N1/15;C12N1/19;C12N1/21;C12N5/10;C12N7/00;C12P21/08 |
主分类号 |
C12N15/09 |
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