Method for monitoring the effect of compounds on Foxc2 expression

摘要

The present invention relates to a method for monitoring/detecting compounds capable to regulate the transcription and/or expression of the forkhead transcription factor Foxc2, which compounds may be useful for the treatment of obesity related diseases and diabetes. The screening for the compounds has been performed in recombinant mouse cells containing the Foxc2 gene and the beta -galactosidase gene in a suitable targeting vector.