发明名称 |
PROCESS FOR PRODUCING MACROLIDE COMPOUND |
摘要 |
It is intended to provide a novel process for producing a 12-membered macrolide compound 11107D having an antitumor activity via biological conversion. The 12-membered macrolide compound 11107B represented by the formula (I), which is a starting substance, is incubated in the presence of a strain capable of converting it into the compound 11107D represented by the formula (II) and belonging to the genus Mortierella or Streptomyces or the family of Micromonosporaceae(for example, Streptomyces sp. AB-1704 strain (FERM BP-8551)) or a cultured cell preparation thereof together with oxygen and then the target compound 11107D is harvested from the incubation medium.
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申请公布号 |
KR20050086873(A) |
申请公布日期 |
2005.08.30 |
申请号 |
KR20057009524 |
申请日期 |
2005.05.26 |
申请人 |
MERCIAN CORPORATION;EISAI CO., LTD. |
发明人 |
OKUDA AKIFUMI;YAMAMOTO SATOSHI;SAKAI TAKASHI;TAKEDA SUSUMU;NAKASHIMA TAKASHI;KANEKO KATSURA;SAMESHIMA TOMOHIRO;KATO TAIRA;KAWAMURA NAOTO |
分类号 |
A61K31/336;A61P35/00;C07D407/06;C12P17/16;(IPC1-7):C12P17/16 |
主分类号 |
A61K31/336 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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