发明名称 Prevention of apoptosis in non-cancerous cells
摘要 Treatment of normal, non-cancerous, animal cells with an agent that depletes polyamines within the cells results in an inhibition of apoptosis when the cells are exposed to an inducer of apoptosis. This inhibition of apoptosis is not observed, or is observed to a lesser extent, in similarly treated cancerous cells. The method of the invention is useful in obtaining preferential killing of cancer cells, as opposed to normal cells, due to anti-cancer therapy.
申请公布号 US6936637(B2) 申请公布日期 2005.08.30
申请号 US20020263402 申请日期 2002.10.01
申请人 UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION 发明人 JOHNSON LEONARD R.;RAY RAMESH M.;VIAR MARY JANE
分类号 A61K31/155;A61K31/195;A61K31/235;(IPC1-7):A61K31/195 主分类号 A61K31/155
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