发明名称 |
METHOD OF TREATMENT OF MYOCARDIAL INFARCTION |
摘要 |
<p>Myocardial infarction in a mammal is treated by administering to the mammal a therapeutically effective amount of a chemical Src family tyrosine kinase protein inhibitor and the use of such inhibitor compounds for the preparation of a medicament for treating myocardial infarction. Myocardial infarction can be prevented by administering to the mammal a prophylactic amount of the inhibitor. The inhibitor preferably is an inhibitor of Src protein selected from the group consisting of a pyrazolopyrimidine class Src family tyrosine kinase inhibitor, a macrocyclic dienone class Src family tyrosine kinase inhibitor, a pyrido[2,3-d]pyrimidine class Src family tyrosine kinase inhibitor, a 4- anilino-3-quinolinecarbonitrile class Src family tyrosine kinase inhibitor, and a mixture thereof. The Src family tyrosine kinase inhibitors can be used to prepare medicaments for the treatment of myocardial infarction. Also disclosed are articles of manufacture containing a chemical Src family tyrosine kinase inhibitor.</p> |
申请公布号 |
KR20050086698(A) |
申请公布日期 |
2005.08.30 |
申请号 |
KR20057008850 |
申请日期 |
2003.11.18 |
申请人 |
THE SCRIPPS RESEARCH INSTITUTE |
发明人 |
CHERESH DAVID A.;PAUL ROBERT;ELICEIRI BRIAN |
分类号 |
A61K38/43;A01K67/027;A61K31/519;A61K31/7088;A61K35/76;A61K38/45;A61K48/00;A61P7/00;A61P9/08;A61P9/10;A61P17/06;A61P19/02;A61P27/02;A61P29/00;A61P35/00;A61P37/02;A61P43/00;(IPC1-7):A61K31/519;A61K31/704 |
主分类号 |
A61K38/43 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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