USE OF A COMBINATION CONTAINING A NON-NUCLEOSIDE REVERSE TRANSCRIPTASE INHIBITOR(NNRTI) WITH AN INHIBITOR OF CYTOCHROME P450, SUCH AS PROTEASE INHIBITORS

摘要

An improved method for using a NNRTI in the treatment of HIV-1 infection, comprising administering to a human, needing treatment for HIV- 1 infection, a therapeutically effective amount of said NNRTI or a pharmaceutically acceptable salt thereof, and an amount of an inhibitor of the cytochromes P450 that is sufficient to elevate, enhance, or extend plasma concentrations of said NNRTI.