发明名称 EXON 1beta OF PDGF RECEPTOR alpha GENE AND UTILIZATION THEREOF
摘要 Using an antisense nucleotide, a ribozyme, a maxyzine or an RNAi constructed based on the base sequence of exon 1beta of a PDGF receptor alpha gene, which is expressed in specific cancer cells, or a polypeptide fragment thereof, the translation of an mRNA transcribed from the exon 1beta of the PDGF receptor alpha gene is inhibited. An expression inhibitor having as the active ingredient a substance inhibiting expression (for example, the antisense nucleotide, ribozyme, maxyzine or an RNAi as described above) is efficacious as a remedy for cancer.
申请公布号 KR20050085006(A) 申请公布日期 2005.08.29
申请号 KR20057008784 申请日期 2005.05.16
申请人 KEIO UNIVERSITY 发明人 IMOTO MASAYA;MINATO YUSUKE;TASHIRO ETSU
分类号 A61K31/7088;A61P35/00;A61P43/00;C12N15/113;C12N15/12;(IPC1-7):C12N15/12;A61K31/708;A61K48/00 主分类号 A61K31/7088
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