发明名称 ЭМУЛЬСИЯ ПЕРФТОРОРГАНИЧЕСКИХ СОЕДИНЕНИЙ С ГАЗОТРАНСПОРТНЫМИ СВОЙСТВАМИ, ПОВЕРХНОСТНО-АКТИВНОЕ ВЕЩЕСТВО ДЛЯ ЭТОЙ ЭМУЛЬСИИ И СПОСОБ ЕЕ ПОЛУЧЕНИЯ
摘要 FIELD: chemical and pharmaceutical industry, colloidal chemistry, in particular production of blood substitutes with gas transmission function of tocopherol polyethylene glycol ester. ^ SUBSTANCE: invention relates to application of tocopherol polyethylene glycol ester application as surfactant to produce emulsion of perfluoroorganic compounds with gas transmission properties. Said emulsion contains 20 % of mixture of perfluoroorcanic compounds comprising perfluorodecaline and perfluoro-n-methylcyclohexyl piperidine in ratio of 2:1 and surfactant such as tocopherol polyethylene glycol ester or mixture thereof with proxanol. Method for production of abovementioned emulsion includes stabilizing of perfluorodecaline and perfluoro-n-methylcyclohexyl piperidine mixture with surfactant such as tocopherol polyethylene glycol ester or mixture thereof with proxanol, and emulsion is produced under homogenization pressure from 20 to 60 MPa with amount of homogenization cycles up to 30. ^ EFFECT: new blood substitutes with gas transmission function. ^ 5 cl, 11 ex, 3 dwg
申请公布号 RU2005100277(A) 申请公布日期 2005.08.27
申请号 RU20050100277 申请日期 2002.09.25
申请人 Общество с ограниченной ответственностью "АКЦЕНТ" (RU) 发明人 Калиниченко Алла Николаевна (RU);Капцов Владимир Васильевич (RU);Лазарев Михаил Иванович (RU)
分类号 A61K9/107;A61K31/025;A61K31/435;A61K47/22 主分类号 A61K9/107
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