发明名称 ФАРМАЦЕВТИЧЕСКИЙ ПРЕПАРАТ И СПОСОБ ЛЕЧЕНИЯ ЗЛОКАЧЕСТВЕННЫХ ОПУХОЛЕЙ У ЧЕЛОВЕКА С ПОМОЩЬЮ АРГИНИНОВОЙ ДЕПРИВАЦИИ
摘要 The present invention provides an isolated and substantially purified recombinant human arginase having sufficiently high enzymatic activity and stability to maintain Adequate Arginine Depletion in a patient. The present invention also provides a pharmaceutical composition comprising the modified invention enzyme and method for treatment of diseases using the pharmaceutical composition.
申请公布号 RU2005101076(A) 申请公布日期 2005.08.27
申请号 RU20050101076 申请日期 2003.06.20
申请人 БАЙО-КЭНСЕР ТРИТМЕНТ ИНТЕРНЭШНЛ ЛИМИТИД (CN) 发明人 ЧЕН Нин Мань (CN);ЛЕУН Юнь Чун (CN);ЛО Вай Хун (CN)
分类号 C12N15/09;A61K9/08;A61K38/00;A61K38/44;A61P35/00;C07H21/04;C12N1/21;C12N9/06;C12N9/14;C12N9/78;C12N9/80;C12N9/96;C12N15/74;C12P21/06;C12R1/125 主分类号 C12N15/09
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