Methods for the production of D-chiro-inositol and the use of D-chiro-inositol obtained therefrom

摘要

Disclosed is a method of producing D-chiro-inositol, comprising: (a) preparing a reaction solution comprising a crude plant extract comprising a D-chiro-inositol precursor containing a D-chiro-inositol moiety selected from D-chiro-inositol, D-pinitol, ciceritol, 1D-2-O-alpha-D-galactopyranose-chiro-inositol, and fagopyritols in a solution of 9N to 12N HCl, and (b) reacting the solution of step (a) at a temperature in the range of 65°C to 110°C for a period of time sufficient to convert the D-chiro-inositol precursor to D-chiro-inositol.