| 发明名称 |
Novel tetrahydropyridines, preparation method and pharmaceutical compositions containing same |
| 摘要 |
Disclosed are compounds of formula (I), wherein: R1 is H, halogen or CF3, R2 and R3 are independently H or methyl, n and n' are independently 0 or 1, A is N or CH, X is S or O, and R4 and R5 are independently H or alkyl. The compounds are used in the manufacture of medicaments for the treatment of mediated by TNF-alpha.
|
| 申请公布号 |
NZ519723(A) |
申请公布日期 |
2005.08.26 |
| 申请号 |
NZ20000519723 |
申请日期 |
2000.12.29 |
| 申请人 |
SANOFI-AVENTIS |
发明人 |
BARONI, MARCO;BOURRIE, BERNARD;CARDAMONE, ROSANA;CASELLAS, PIERRE |
| 分类号 |
A61K;A61K31/343;A61K31/381;A61K31/44;A61K31/4427;A61K31/443;A61K31/4436;A61K31/444;A61K31/445;A61K31/4525;A61K31/4535;A61P;A61P1/00;A61P1/04;A61P3/00;A61P3/10;A61P9/10;A61P11/00;A61P11/06;A61P11/16;A61P13/12;A61P17/00;A61P17/06;A61P19/02;A61P19/08;A61P25/00;A61P25/16;A61P25/28;A61P29/00;A61P31/04;A61P31/12;A61P31/18;A61P33/06;A61P35/00;A61P37/00;A61P37/06;C07D;C07D405/06;C07D405/10;C07D405/14;C07D407/10;C07D409/06;C07D409/10;C07D409/14;(IPC1-7):C07D409/06;A61K31/452;A61K31/453 |
主分类号 |
A61K |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
