发明名称 Sulphinic acid derivatives useful in gastro-reflux disease
摘要 A compound of formula (I) is described to be used in the manufacture of a medicament for the treatment of conditions such as gastro-oesophageal reflux disease (GORD), regurgitation in infants, belching, hyperkinesia, emesis and dyspepsia. R1, R3 and R4 in formula (I) represent hydrogen; and R2 represents hydroxyl, fluoro or an oxo group. The racemate of (3-amino-2-hydroxypropyl)sulphinic acid is an exception. It is disclosed that the compound, racemate or a stereoisomer thereof may exist in the form of a pharmaceutically acceptable salt and/or solvate thereof.
申请公布号 NZ529920(A) 申请公布日期 2005.08.26
申请号 NZ20020529920 申请日期 2002.06.04
申请人 ASTRAZENECA AB 发明人 FITZPATRICK, KEVIN;GEISS, WILLIAM;LEHMANN, ANDERS;SUNDEN, GUNNEL;VON UNGE, SVERKER
分类号 C07D277/74;A61K31/145;A61K31/185;A61P1/00;A61P1/04;A61P1/08;A61P1/14;A61P11/00;A61P11/06;A61P25/32;A61P25/34;A61P25/36;C07C313/04;C07D277/76;(IPC1-7):C07C313/02;A61K31/195;A61P25/30 主分类号 C07D277/74
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