| 发明名称 |
Serine protease inhibitors |
| 摘要 |
Compounds having the structure shown below are useful to inhibit serine protease enzymes, such as TF/factor VIIa, factor Xa, thrombin and kallikrein. These compounds may be used in methods of preventing and/or treating clotting disorders.
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| 申请公布号 |
US2005186198(A1) |
申请公布日期 |
2005.08.25 |
| 申请号 |
US20050088511 |
申请日期 |
2005.03.24 |
| 申请人 |
GENENTECH, INC. |
发明人 |
ALIAGAS-MARTIN IGNACIO;ARTIS DEAN R.;DINA MICHAEL S.;FLYGARE JOHN A.;GOLDSMITH RICHARD A.;MUNROE REGINA A.;OLIVERO ALAN G.;PASTOR RICHARD;RAWSON THOMAS E.;ROBARGE KIRK D.;SUTHERLIN DANIEL P.;WEESE KENNETH J.;ZHOU AIHE;ZHU YAN |
| 分类号 |
C07D333/34;A61K31/18;A61K31/196;A61K31/216;A61K31/381;A61P7/02;A61P9/10;C07C257/18;C07C311/05;C07C311/08;C07C311/13;C07C311/18;C07C311/29;C07C311/51;(IPC1-7):A61K38/48;A61K31/60;A61K31/54;A61K31/445 |
主分类号 |
C07D333/34 |
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